岡田俊平 (Shunpei OKADA)

講師

博士（工学）

[専門]　RNA生物学、ウイルス学

論文

1. Liu Y, Tumurgan Z, Wai AP, Akter M, Wadi AFAA, Mizukami Y, Wada M, Okada S, Niino D, Murata T, Iizasa H, Yoshiyama H. SFK inhibition suppresses EBV-encoded BART miRNAs and induces apoptosis in EBV-positive gastric epithelial cells. Cancers 18(7):1082(2026)
2. Muchtar A, Onomura D, Ding D, Nishitsuji H, Shimotono K, Okada S, Ueda K, Watashi K, Wakita T, Iida K, Yoshiyama H, Iizasa H. MicroRNA-3145 as a Potential Therapeutic Target for Hepatitis B Virus: Inhibition of Viral Replication via Downregulation of HBS and HBX. Front Microbiol 15:1499216 (2025)
3. PhyoWai A, Richardo T, Wakae K, Okada S, Tumurgan Z, Muramatsu M, Yoshiyama H, Iizasa H. Epstein-Barr virus infection induces mitochondrial DNA mutations via APOBEC3C expression in gastric epithelial cells. Microbiol Immunol 69(3):157-167 (2025)
4. Liu Y, PhyoWai A, Iida Y, Tumurgan Z, Okada S, Iizasa H, Yoshiyama H. Exploring the anti-EBV potential of suberoylanilide hydroxamic acid: leading apoptosis in infected cells by suppressing BART gene expression and inducing lytic infection. Virology　597:110161 (2024)
5. Wadi AFAA, Onomura D, Funamori H, Khatun MM, Okada S, Iizasa H, Yoshiyama H. Effect of strain differences, humidity changes, and saliva contamination on inactivation of SARS-CoV-2 by ions. Viruses 16(4):520 (2024)
6. Yang Y, Nakayama K, Okada S, Sato K, Wada T, Sakaguchi Y, Murayama A, Suzuki T, Sakurai M. ICLAMP: a novel technique to explore adenosine deamination via inosine chemical labeling and affinity molecular purification. FEBS Lett 598(9):1080-1093 (2024).
7. Iizasa H, Kartika AV, Kebede SF, Okada S, Onomura D, Wadi AFAA, Khatun MM, Moe TM, Nishikawa J, Yoshiyama H. Development of EBV-associated gastric cancer: infection, inflammation, and oncogenesis. World J Gastroenterol 28(44): 6249-6257 (2022)
8. Noda Y, Okada S, Suzuki T. Regulation of A-to-I RNA editing and stop codon recoding to control selenoprotein expression during skeletal myogenesis. Nat Commun 13(1):2503 (2022
9. Yang Y, Okada S, Sakurai M. Adenosine-to-inosine RNA editing in neurological development and disease. RNA Biol 18(7):999-1013 (2021)
10. Sakurai M, Okada S, Ueda H, Yang Y. Discovering A-to-I RNA Editing Through Chemical Methodology “ICE-seq”. Methods Mol Biol 2181:113-148 (2021)
11. Suzuki T, Yashiro Y, Kikuchi I, Ishigami Y, Saito H, Matsuzawa I, Okada S, Mito M, Iwasaki S, Ma D, Zhao X, Asano K, Lin H, Kirino Y, Sakaguchi Y, Suzuki T. Complete chemical structures of human mitochondrial tRNAs. Nat Commun 11(1):4269 (2020)
12. Hojo H, Yashiro Y, Noda Y, Ogami K, Yamagishi R, Okada S, Hoshino SI, Suzuki T. The RNA-binding protein QKI-7 recruits the poly(A) polymerase GLD-2 for 3′ adenylation and selective stabilization of microRNA-122. J Biol Chem 295(2):390-402 (2020)
13. Okada S, Ueda H, Noda Y, Suzuki T Transcriptome-wide identification of A-to-I RNA editing sites using ICE-seq. Methods 156:66-78 (2019)
14. Uchida H, Matsumura S, Okada S, Suzuki T, Minami T, Ito S. RNA editing enzyme ADAR2 is a mediator of neuropathic pain after peripheral nerve injury. FASEB J 31(5):1847-1855 (2017)
15. Ishida K, Miyauchi K, Kimura Y, Mito M, Okada S, Suzuki T, Nakagawa S.Regulation of gene expression via retrotransposon insertions and the noncoding RNA 4.5S RNAH. Genes Cells 20(11):887-901 (2015)
16. Okada S, Sakurai M, Ueda H, Suzuki T. Biochemical and Transcriptome-Wide Identification of A-to-I RNA Editing Sites by ICE-Seq. Methods Enzymol 560:331-353 (2015)
17. Suzuki T, Ueda H, Okada S, Sakurai M. Transcriptome-wide identification of adenosine-to-inosine editing using the ICE-seq method. Nat Protoc 10(5):715-732 (2015)
18. Sakurai M, Ueda H, Yano T, Okada S, Terajima H, Mitsuyama T, Toyoda A, Fujiyama A, Kawabata H, Suzuki T.A biochemical landscape of A-to-IRNA editing in the human brain transcriptome. Genome Res 24(3):522-534 (2014)

招待講演

1. Iizasa H, Liu Y, Akter M, Okada S, Wada M, Yoshiyama H. Will EBV-derived microRNA be a therapeutic target?The First CAEBV International Symposium. Tokyo (Institute of Science, Tokyo), Japan, March 20-21, (2026)
2. Iizasa H, Akter M, Wada M, Okada S. Elucidation of the SARS-CoV-2 replication mechanism and its therapeutic applications. Japan-India Global Education and Research Center (JIGER) kick off meeting. Matsue (Kunibiki Messe), Japan. February 27-28. (2026)